Rejuvenate Your Skin with

Polynucleotide Treatments

Polynucleotide Treatments: Cutting-Edge Cellular Regeneration Technology

Repair Damage, Boost Collagen, Reveal Vibrant Skin

Experience next-level skincare innovation with polynucleotide (PNR) therapy – a ground-breaking treatment that stimulates collagen, repairs damage, and renews your skin from within.

Unlike surface-level treatments, polynucleotides work at a cellular level to repair damaged skin cells, stimulate collagen production, and drive deep skin regeneration. From acne and rosacea to age spots, sun damage, fine lines, and uneven texture, this versatile treatment addresses multiple concerns across the face, neck, décolletage, and body.

Quick, effective, and suitable for all skin types, polynucleotide treatments deliver maximum results with minimal downtime. Featured in Vogue, Bazaar, and Women’s Health, it’s the celebrity-trusted secret to long-lasting, natural radiance you can finally access.

Select Your Polynucleotide Treatment

From targeted areas to full-face rejuvenation, we offer cutting-edge treatments for cellular skin regeneration.

Plenhyage XL
3 for £700£270
Harness the power of next-generation skin regeneration with Plenhyage XL. This cutting-edge polynucleotide-based treatment works deep within the skin to stimulate collagen, repair tissue, and restore elasticity. Ideal for fine lines, wrinkles, sun damage, and scarring, Plenhyage XL helps strengthen and rejuvenate your skin from the inside out, leaving you with a firmer, smoother, and more radiant complexion.

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Plinest® (Full Face)
3 for £780£275
Smooths fine lines and restores volume; 3 course recommended

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Plinest® (Under Eyes)
3 for £700£250
Targeted treatment to smooth and restore volume under the eyes

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Vitaran (Full Face)
3 for £600£220
Polynucleotide booster for collagen, elastin & hydration

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Vitaran (Under Eyes / Small Area)
3 for £500£180
Targeted polynucleotide treatment for delicate areas

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Polynucleotide Under-Eye Treatment
3 for £699£275
Say goodbye to dark circles, fine lines, and tired-looking eyes with our Polynucleotide Under-Eye Treatment. Specially designed for the delicate eye area, this treatment hydrates, brightens, and tightens the skin, reducing the appearance of hollows and fatigue. Wake up to refreshed, revitalised eyes every day.

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Polynucleotide Skin Booster - 2ml
3 for £699£275
Experience next-level skin rejuvenation with our Polynucleotide Skin Booster. This advanced treatment stimulates collagen production, deeply hydrates, and repairs skin at a cellular level. Ideal for tired, dull, or ageing skin, it restores elasticity and radiance, leaving you with a smooth, youthful glow.

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Sculptra® Collagen Stimulator

Sculptra® Treatment - Single Variant
£400 per vial
Restore lost volume and redefine your features with Sculptra, the injectable that works beneath the surface to stimulate natural collagen production. Unlike traditional fillers, Sculptra delivers gradual, long-lasting results – helping to smooth wrinkles, restore facial contours, and improve skin firmness over time. Perfect for those looking for a subtle, natural rejuvenation, this treatment enhances volume while improving overall skin quality. All treatments include a personalised consultation and clinical assessment.

Sculptra treatment courses are available as 1 vial / 1 session, which is ideal for minor volume correction or as a first treatment, 2 vials / 2 sessions, which is recommended for moderate facial rejuvenation, or 3 vials / 3 sessions, which provides a comprehensive course for full facial support.

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Maintenance / Top-Up Vial
£400
As needed after initial course

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Polynucleotide Treatments At a Glance

Treatment Time

15-30 minutes

Expected Results

Visible improvements noticeable after the first few treatments, with best results after 4 weeks.

Side Effects

Minor redness, swelling, or bruising at the injection sites, which goes within a few days.

Recovery

No significant downtime; normal activities can resume immediately.

Anaesthetic

Typically not required; optional topical anaesthetic for comfort.

Costs

From £250

Ready to Experience Next-Level Skin Regeneration?

Book your consultation today. Our practitioners will create your personalised Plenhyage XL journey.

Polynucleotide Treatment FAQs

Your Questions, Answered

What exactly are polynucleotides?

Polynucleotides (PDRN) are DNA-based molecules that work at a cellular level to stimulate tissue repair and regeneration. Unlike hyaluronic acid which hydrates, polynucleotides actually repair damaged skin cells, boost collagen production, and improve overall skin health. Think of them as your skin’s natural repair system, enhanced and concentrated for maximum effectiveness.

How is this different from Profhilo?

Profhilo focuses on hydration and elasticity using hyaluronic acid, providing instant plumping and moisture. Polynucleotides work deeper, repairing skin at a cellular level and stimulating long-term regeneration. Profhilo gives you immediate glow and hydration, whilst polynucleotides rebuild your skin’s foundation for lasting improvements. Some clients combine both for comprehensive rejuvenation.

What skin concerns can polynucleotides treat?

Polynucleotides are brilliant for fine lines, wrinkles, sun damage, scarring, uneven texture, dullness, and general signs of ageing. They’re particularly effective for under-eye concerns, improving dark circles, crepey skin, and fine lines. They also help with acne scarring, rosacea, and skin laxity. The treatment strengthens and rejuvenates skin from within.

Is there any downtime after treatment?

Minimal! You might experience slight redness, swelling, or bruising at injection sites for a day or two, but most clients return to normal activities immediately. We recommend avoiding makeup, exercise, and alcohol for 24 hours. Unlike more aggressive treatments, polynucleotides offer significant improvements without disrupting your busy lifestyle.

What's Sculptra and how does it differ?

Sculptra is a collagen stimulator that gradually restores facial volume over time, rather than providing immediate results like traditional fillers. It stimulates your body’s natural collagen production for subtle, long-lasting improvements (up to two years). Whilst polynucleotides focus on skin quality and repair, Sculptra addresses structural volume loss. We’ll recommend the best option during consultation.

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Polynucleotide Treatments

Next-level skincare innovation, harnessing polynucleotides (PDR) to rejuvenate skin, reduce signs of ageing, and achieve a vibrant, refreshed appearance.